Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731345 | 0.79 | TSHR (0.38) | PTPN1BLMMEN1CYP3A4ALOX15 | |
| SCHEMBL28929622 | 0.79 | LMNA (0.54) | PTPN1BLMMEN1CYP3A4ALOX15 | |
| SCHEMBL11869933 | 0.79 | ALDH1A1 (0.42) | MEN1CYP3A4KMT2AALDH1A1TSHR | |
| SCHEMBL6762246 | 0.77 | TSHR (0.42) | PTPN1BLMMEN1CYP3A4ALOX15 | |
| SCHEMBL11869388 | 0.76 | ALDH1A1 (0.37) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL11392320 | 0.73 | SLC6A2 (0.33) | BLMMEN1KMT2ATSHR | |
| SCHEMBL11662426 | 0.72 | TSHR (0.43) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL7911936 | 0.71 | MEN1 (0.33) | BLMMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL28599126 | 0.71 | TSHR (0.41) | PTPN1BLMMEN1CYP3A4ALOX15 | |
| SCHEMBL8366203 | 0.71 | TSHR (0.38) | BLMMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140314826-A1 | NOVEL POLYMERS WHICH RESIST BACTERIAL ATTACHMENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-10-23 | — | — | US | disclosed |