Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | NQO2 | P16083 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | BCR | P11274 | 3/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16192001 | 1.00 | CYP1A1 (0.53) | CYP1A1CYP1B1NQO2KDM4EMEN1 | |
| SCHEMBL16307443 | 0.88 | KDM4E (0.48) | CYP1A1CYP1B1NQO2KDM4EMEN1 | |
| SCHEMBL22525859 | 0.88 | CYP1A1 (0.61) | CYP1A1CYP1B1NQO2KDM4EMEN1 | |
| SCHEMBL28140894 | 0.87 | RELA (0.56) | NQO2CYP19A1TUBB4ATUBBTUBA3C | |
| SCHEMBL9954124 | 0.84 | TRPA1 (0.63) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL3848013 | 0.84 | TRPA1 (0.63) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL28403833 | 0.83 | CYP19A1 (0.65) | CYP1A1CYP1B1NQO2KDM4EMEN1 | |
| SCHEMBL15105021 | 0.81 | TRPA1 (0.63) | CYP1A1CYP1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL3869325 | 0.81 | TRPA1 (0.63) | CYP1A1CYP1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29288278 | 0.80 | GRIN1 (0.56) | KDM4EMEN1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796442-B1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2019-03-27 | — | — | EP | claimed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | claimed |
| EP-2796442-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2014-10-29 | — | — | EP | claimed |
| EP-2796442-B1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2019-03-27 | — | — | EP | disclosed |
| EP-2796442-B1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2019-03-27 | — | — | EP | disclosed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | disclosed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | disclosed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | disclosed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | disclosed |
| EP-2796442-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2014-10-29 | — | — | EP | disclosed |
| EP-2796442-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2014-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | ACHE, GAP43, LNPK | CYP1A1 2551/4885CYP1B1 2811/4885NQO2 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.