SCHEMBL16192530

SCHEMBL16192530

CCO[Si](CC)(CCCNC1CCCCC1)OCC

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 9/20 0.38
KDM4E B2RXH2 2/20 0.38
CXCL12 P48061 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
HRH4 Q9H3N8 5/20 0.35
HRH3 Q9Y5N1 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132342 0.83 CXCR4 (0.40) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL778037 0.82 CXCR4 (0.39) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL32678387 0.82 CXCR4 (0.39) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL32678386 0.82 CXCR4 (0.39) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL16192599 0.80 KDM4E (0.34) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL730245 0.79 CXCR4 (0.37) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL27841107 0.79 CXCR4 (0.37) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL15367114 0.79 ALDH1A1 (0.42) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL15360810 0.77 CXCR4 (0.39) CXCR4KDM4ECXCL12ALDH1A1CYP1A2
SCHEMBL555892 0.76 KDM4E (0.41) CXCR4KDM4ECXCL12ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN claimed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US claimed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP claimed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US claimed
EP-3157970-A1 SILYLATED POLYURETHANES Huntsman International LLC (US) 2017-04-26 EP claimed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP claimed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO claimed
US-20220220247-A1 Composition Comprising Silylated Polymer HUNTSMAN INTERNATIONAL LLC 2022-07-14 US disclosed
EP-3976707-A1 COMPOSITION COMPRISING SILYLATED POLYMER Huntsman International LLC (US) 2022-04-06 EP disclosed
CN-113966360-A Compositions comprising silylated polymers 亨茨曼国际有限公司 2022-01-21 CN disclosed
WO-2020239746-A1 COMPOSITION COMPRISING SILYLATED POLYMER HUNTSMAN INTERNATIONAL LLC (US) 2020-12-03 WO disclosed
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN disclosed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US disclosed
EP-3157970-A1 SILYLATED POLYURETHANES Huntsman International LLC (US) 2017-04-26 EP disclosed
EP-2989155-A1 COMPOSITION COMPRISING SILYLATED POLYMERS Huntsman International LLC (US) 2016-03-02 EP disclosed
US-20160046793-A1 Composition Comprising Silylated Polymers HUNTSMAN INTERNATIONAL LLC 2016-02-18 US disclosed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP disclosed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO disclosed
WO-2014173638-A1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2014-10-30 WO disclosed
EP-2796493-A1 Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane HUNTSMAN INTERNATIONAL LLC (US) 2014-10-29 EP disclosed