SCHEMBL16192599

SCHEMBL16192599

CCO[Si](CC)(CNC1CCCCC1)OCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.34
ALDH1A1 P00352 4/20 0.34
POLB P06746 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
TSHR P16473 1/20 0.31
MITF O75030 1/20 0.31
DPP7 Q9UHL4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6056865 0.83 KDM4E (0.37) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL141765 0.81 KDM4E (0.36) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL16192530 0.80 CXCR4 (0.38) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL4449821 0.79 KDM4E (0.35) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL123835 0.79 KDM4E (0.35) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL20495376 0.79 KDM4E (0.37) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL1455088 0.75 KDM4E (0.34) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL3898432 0.75 EPHX1 (0.36)
SCHEMBL3903032 0.74 KDM4E (0.32) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL3633450 0.73 KDM4E (0.43) KDM4EALDH1A1MEN1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN claimed
EP-2111483-B1 CORROSION INHIBITOR ASCOTEC (FR) 2020-04-29 EP claimed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US claimed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP claimed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US claimed
EP-3157970-A1 SILYLATED POLYURETHANES Huntsman International LLC (US) 2017-04-26 EP claimed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP claimed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO claimed
CN-101600816-B Corrosion inhibitor ASCOTEC 2012-09-05 CN claimed
CN-101600816-A Corrosion inhibitor ASCOTEC (FR) 2009-12-09 CN claimed
US-20220220247-A1 Composition Comprising Silylated Polymer HUNTSMAN INTERNATIONAL LLC 2022-07-14 US disclosed
CN-113966360-A Compositions comprising silylated polymers 亨茨曼国际有限公司 2022-01-21 CN disclosed
WO-2020239746-A1 COMPOSITION COMPRISING SILYLATED POLYMER HUNTSMAN INTERNATIONAL LLC (US) 2020-12-03 WO disclosed
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN disclosed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US disclosed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP disclosed
WO-2014173638-A1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2014-10-30 WO disclosed
EP-2796493-A1 Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane HUNTSMAN INTERNATIONAL LLC (US) 2014-10-29 EP disclosed
CN-101600816-B Corrosion inhibitor ASCOTEC 2012-09-05 CN disclosed
CN-101600816-A Corrosion inhibitor ASCOTEC (FR) 2009-12-09 CN disclosed