Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.59 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.59 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.46 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18513031 | 0.84 | ANPEP (0.52) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| Hydrochloric Acid SCHEMBL16972962 | 0.84 | ANPEP (0.57) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| SCHEMBL9965943 | 0.83 | ANPEP (0.50) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| SCHEMBL23639991 | 0.83 | ANPEP (0.46) | ANPEPDNPEPRNPEP | |
| SCHEMBL16972960 | 0.81 | ANPEP (0.46) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| SCHEMBL30997680 | 0.81 | ANPEP (0.62) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| SCHEMBL11129 | 0.79 | ANPEP (0.55) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| SCHEMBL1277891 | 0.79 | ANPEP (0.68) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| SCHEMBL1277892 | 0.79 | ANPEP (0.68) | ANPEPDNPEPRNPEPCAPN1CAPN9 | |
| SCHEMBL14067667 | 0.79 | ANPEP (0.68) | ANPEPDNPEPRNPEPCAPN1CAPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365615-B2 | Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method | JITSUBO CO., LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-20120088848-A1 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-04-12 | — | — | US | disclosed |
| US-20120088848-A1 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-04-12 | — | — | US | disclosed |
| US-7968519-B2 | Amido-containing metal complexes; sonication; for self-assembling polypeptides; vesicles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-28 | — | — | US | disclosed |
| US-7968519-B2 | Amido-containing metal complexes; sonication; for self-assembling polypeptides; vesicles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-28 | — | — | US | disclosed |
| US-20080125581-A1 | Methods and compositions for controlled polypeptide synthesis | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2008-05-29 | — | — | US | disclosed |
| US-20080125581-A1 | Methods and compositions for controlled polypeptide synthesis | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2008-05-29 | — | — | US | disclosed |
| US-7329727-B2 | Methods and compositions for controlled polypeptide synthesis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329727-B2 | Methods and compositions for controlled polypeptide synthesis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088848-A1 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS | NGLY1, LNPEP, NPPA | ANPEP 4/4885DNPEP 5/4885RNPEP 16/4885 |
| US-20080125581-A1 | Methods and compositions for controlled polypeptide synthesis | NGLY1, LNPEP, NPPA | ANPEP 4/4885DNPEP 5/4885RNPEP 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.