Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862918 | 0.89 | MAPT (0.39) | MAPTDPP4KDRKDM4ESMN1; SMN2 | |
| SCHEMBL862853 | 0.88 | MAPKAPK2 (0.39) | MAPTDPP4KDRKDM4ESMN1; SMN2 | |
| SCHEMBL7841063 | 0.80 | MAPT (0.42) | MAPTKDM4ESMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL18952507 | 0.78 | MAPT (0.43) | MAPTDPP4KDRKDM4ESMN1; SMN2 | |
| SCHEMBL6877174 | 0.78 | ALDH1A1 (0.49) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL16400707 | 0.77 | KDM4E (0.44) | MAPTDPP4KDRKDM4ESMN1; SMN2 | |
| SCHEMBL12067848 | 0.75 | ALDH1A1 (0.43) | MAPTNFKB1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL15537688 | 0.75 | MAPT (0.42) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL863038 | 0.75 | ALDH1A1 (0.39) | DPP4KDRKDM4ESMN1; SMN2TSHR | |
| SCHEMBL1619623 | 0.75 | ALDH1A1 (0.39) | DPP4KDRKDM4ESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088913-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED-8-ALKOXY[1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-2-AMINES | DOW AGROSCIENCES LLC (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088913-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED-8-ALKOXY[1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-2-AMINES | PAH, AZI2, ABL2 | MAPT 2607/4885DPP4 663/4885FOS 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.