SCHEMBL1619618

SCHEMBL1619618

CCCCCC(CC)NCCCCO

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 5/20 0.44
ALDH1A1 P00352 5/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CNR1 P21554 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ADRA1A P35348 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ABCC3 O15438 1/20 0.42
EPHX1 P07099 1/20 0.37
NAAA Q02083 1/20 0.35
DPP7 Q9UHL4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1619615 0.98 LMNA (0.48) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1619918 0.94 LMNA (0.45) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL9949435 0.94 LMNA (0.45) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL117119 0.92 LMNA (0.44) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1618085 0.92 LMNA (0.44) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL9950238 0.88 LMNA (0.46) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1619560 0.88 LMNA (0.46) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1619940 0.88 LMNA (0.46) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL24353239 0.88 EPHX1 (0.48) SMN1; SMN2LMNAALDH1A1TSHRCNR1
SCHEMBL9541689 0.88 EPHX1 (0.48) SMN1; SMN2LMNAALDH1A1TSHRCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP claimed
CN-100349854-C Method for producing (meth) acrylic acid esters BASF AG (DE) 2007-11-21 CN claimed
US-7268251-B2 Method for producing (meth) acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-09-11 US claimed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US claimed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP claimed
US-10174349-B2 Recombinant cell producing 2-hydroxyisobutyric acid EVONIK ROEHM GMBH (DE) 2019-01-08 US disclosed
US-8207371-B2 Process for preparing (meth)acrylic acid EVONIK RÖHM GMBH (DE) 2012-06-26 US disclosed
US-20110171702-A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2011-07-14 US disclosed
US-7928251-B2 Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH (DE) 2011-04-19 US disclosed
US-20100029979-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID EVONIK ROEHM GMBH (DE) 2010-02-04 US disclosed
US-20100010276-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK ROEHM GMBH (DE) 2010-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029979-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID MMAB, ASS1, PAM SMN1; SMN2 3577/4885LMNA 3634/4885ALDH1A1 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.