Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403846 | 1.00 | PAOX (0.59) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL1403872 | 1.00 | PAOX (0.59) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL1619610 | 1.00 | PAOX (0.59) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL5880368 | 1.00 | PAOX (0.59) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL20231224 | 1.00 | PAOX (0.59) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL1404033 | 1.00 | PAOX (0.59) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL25387214 | 0.98 | PAOX (0.55) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL9368 | 0.98 | PAOX (0.55) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL8866 | 0.90 | PAOX (0.52) | PAOXSIGMAR1USP2ALDH1A1HPGD | |
| SCHEMBL11899867 | 0.90 | HRH3 (0.52) | PAOXHRH3GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399409-B1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF SE (DE) | 2012-10-31 | — | — | EP | claimed |
| EP-1399408-B1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF AG (DE) | 2006-03-22 | — | — | EP | claimed |
| US-10174349-B2 | Recombinant cell producing 2-hydroxyisobutyric acid | EVONIK ROEHM GMBH (DE) | 2019-01-08 | — | — | US | disclosed |
| EP-2291530-B1 | RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID | EVONIK ROEHM GMBH (DE) | 2018-12-26 | — | — | EP | disclosed |
| CN-107083352-A | Produce the recombinant cell of 2 hydroxy-iso-butyric acids | 赢创罗姆有限公司 | 2017-08-22 | — | — | CN | disclosed |
| EP-2125771-B1 | PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE | EVONIK ROEHM GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-8207371-B2 | Process for preparing (meth)acrylic acid | EVONIK RÖHM GMBH (DE) | 2012-06-26 | — | — | US | disclosed |
| US-20110171702-A1 | RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID | EVONIK ROEHM GMBH (DE) | 2011-07-14 | — | — | US | disclosed |
| US-7928251-B2 | Process for preparing tetramethyl glycolide | EVONIK ROEHM GMBH (DE) | 2011-04-19 | — | — | US | disclosed |
| US-20100029979-A1 | PROCESS FOR PREPARING (METH)ACRYLIC ACID | EVONIK ROEHM GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| US-20100010276-A1 | PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE | EVONIK ROEHM GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2125771-A1 | PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE | Evonik Röhm GmbH (DE) | 2009-12-02 | — | — | EP | disclosed |
| EP-2091906-A1 | PROCESS FOR PREPARING (METH)ACRYLIC ACID | Evonik Röhm GmbH (DE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008061819-A1 | PROCESS FOR PREPARING (METH)ACRYLIC ACID | EVONIK RÖHM GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008061821-A1 | PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE | EVONIK RÖHM GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029979-A1 | PROCESS FOR PREPARING (METH)ACRYLIC ACID | MMAB, ASS1, PAM | PAOX 1668/4885SIGMAR1 4037/4885HRH3 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.