Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197460 | 0.99 | TDP1 (0.67) | TDP1ALDH1A1POLBKMT2AHTT | |
| SCHEMBL16197442 | 0.88 | ALDH1A1 (0.69) | TDP1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL16197615 | 0.86 | CYP3A4 (0.52) | TDP1ALDH1A1POLBKMT2AHTT | |
| SCHEMBL16197383 | 0.80 | POLB (0.84) | TDP1ALDH1A1POLBKMT2AHTT | |
| SCHEMBL25320235 | 0.78 | HDAC6 (0.55) | ALDH1A1KMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL12793844 | 0.77 | TDP1 (0.72) | TDP1ALDH1A1POLBKMT2AHTT | |
| SCHEMBL14056771 | 0.77 | MAPT (0.59) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL16197394 | 0.76 | LMNA (0.60) | ALDH1A1KMT2AHTTMEN1GLA | |
| SCHEMBL12793858 | 0.76 | TDP1 (0.69) | TDP1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL16197436 | 0.75 | LMNA (0.58) | ALDH1A1KMT2AHTTMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |