Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197460 | 0.89 | TDP1 (0.67) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL16208828 | 0.88 | TDP1 (0.69) | ALDH1A1KMT2AMEN1GAANPC1 | |
| SCHEMBL16197615 | 0.84 | CYP3A4 (0.52) | ALDH1A1KMT2AMEN1MAPK1TDP1 | |
| SCHEMBL16197498 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL12793846 | 0.79 | KMT2A (0.72) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL28371395 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL14696849 | 0.76 | GLA (0.74) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL14697021 | 0.76 | KMT2A (0.72) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL334552 | 0.74 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL25320235 | 0.74 | HDAC6 (0.55) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |