Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197383 | 0.86 | POLB (0.84) | ALDH1A1KMT2AMEN1GAAPOLB | |
| SCHEMBL12793846 | 0.83 | KMT2A (0.72) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL14697021 | 0.83 | KMT2A (0.72) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL1832768 | 0.82 | L3MBTL1 (0.72) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL16197442 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL16085419 | 0.79 | GAA (1.00) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL16919774 | 0.78 | KMT2A (0.90) | ALDH1A1KMT2AMEN1MAPK1GAA | |
| SCHEMBL12793245 | 0.78 | POLB (0.88) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL16197408 | 0.78 | TDP1 (0.58) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL334552 | 0.78 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014173904-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY | VIB VZW (BE) | 2014-10-30 | — | — | WO | disclosed |