Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 11/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092497 | 0.82 | BPTF (0.31) | BPTF | |
| SCHEMBL12871802 | 0.77 | GAA (0.45) | POLBGLSALDH1A1LMNAMAPT | |
| SCHEMBL31582398 | 0.76 | GAA (0.37) | NMT1 | |
| SCHEMBL13184159 | 0.75 | POLB (0.39) | POLBGLSALDH1A1LMNAMAPT | |
| SCHEMBL13683200 | 0.68 | POLB (0.36) | NMT1POLBGLSALDH1A1LMNA | |
| SCHEMBL16200079 | 0.68 | KDM4E (0.40) | GLSALDH1A1LMNABPTF | |
| SCHEMBL13784458 | 0.66 | — | — | |
| SCHEMBL1196791 | 0.66 | — | — | |
| SCHEMBL16200399 | 0.65 | SIGMAR1 (0.39) | NMT1POLBLMNA | |
| SCHEMBL16200064 | 0.65 | CYP2A13 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |