Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996606 | 0.83 | GRM5 (0.48) | BACE1ATMALDH1A1LMNATGFBR1 | |
| SCHEMBL16200256 | 0.82 | L3MBTL1 (0.45) | CNR1CNR2GPR55ALDH1A1LMNA | |
| SCHEMBL14139215 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPK14NR3C1KDM4E | |
| SCHEMBL12856308 | 0.80 | GRM5 (0.46) | BACE1CNR1CNR2ATMALDH1A1 | |
| SCHEMBL13739115 | 0.80 | ALDH1A1 (0.55) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL13066526 | 0.79 | SLC34A1 (0.51) | GRM5 | |
| SCHEMBL16200248 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNAPTGS2KDM4EKMT2A | |
| SCHEMBL12859331 | 0.78 | ATM (0.41) | BACE1ATMALDH1A1LMNATGFBR1 | |
| SCHEMBL12871642 | 0.78 | KDM4E (0.42) | BACE1ATMALDH1A1LMNAKDM4C | |
| SCHEMBL14996631 | 0.77 | MEN1 (0.43) | CNR1CNR2GPR55ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |