Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12859323 | 0.83 | LMNA (0.38) | MAPK14GRM5KDM4EALDH1A1LMNA | |
| SCHEMBL12859325 | 0.83 | ATM (0.40) | ATMTGFBR1MAPK14KDM4CGRM5 | |
| SCHEMBL12859348 | 0.82 | ALDH1A1 (0.41) | KDM4CKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL12859317 | 0.81 | PDE2A (0.42) | GRM5KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL14996606 | 0.80 | GRM5 (0.48) | ATMTGFBR1MAPK14KDM4CGRM5 | |
| SCHEMBL12859309 | 0.80 | MAPT (0.46) | GRM5KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12859337 | 0.78 | PDE2A (0.46) | GRM5KDM4ENPC1RAB9A | |
| SCHEMBL16200081 | 0.78 | BACE1 (0.45) | ATMTGFBR1MAPK14KDM4CGRM5 | |
| SCHEMBL12871642 | 0.75 | KDM4E (0.42) | ATMKDM4CGRM5KDM4EALDH1A1 | |
| SCHEMBL4343263 | 0.73 | BACE1 (0.52) | ATMKDM4CGRM5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455398-B2 | Amide compounds, preparation methods and uses thereof | SINOCHEM CORPORATION (CN) | 2013-06-04 | — | — | US | disclosed |
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | SINOCHEM CORPORATION | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | ACHE, MGAM, PGLS | ATM 377/4885TGFBR1 2814/4885MAPK14 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.