Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892344 | 0.83 | ALDH1A1 (0.49) | ALOX5ALDH1A1NPC1MAPTALOX15 | |
| SCHEMBL7034638 | 0.81 | ALOX5 (0.53) | ALOX5ALDH1A1MAPK1SMN1; SMN2TBK1 | |
| SCHEMBL10716431 | 0.80 | NUDT1 (0.43) | ALOX5HRH3POLB | |
| SCHEMBL8786266 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1KDM1AMAPTNFKB1MAPK1 | |
| SCHEMBL9394272 | 0.80 | ALOX5 (0.54) | ALOX5ALDH1A1ALOX15FFAR1HSD17B10 | |
| SCHEMBL11135469 | 0.79 | ALOX5 (0.50) | ALOX5ALDH1A1TBK1 | |
| Hydrochloric Acid SCHEMBL10716525 | 0.78 | NUDT1 (0.42) | ALOX5MAPTHRH3POLB | |
| SCHEMBL2632940 | 0.78 | MAPT (0.50) | ALOX5ALDH1A1KDM1ANPC1MAPT | |
| SCHEMBL8493143 | 0.78 | ALOX5 (0.69) | ALOX5ALDH1A1NPC1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL27410606 | 0.76 | ALOX5 (0.67) | ALOX5ALDH1A1NPC1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013187-B1 | DIARYLTHIOHYDANTOIN COMPOUNDS | UNIV CALIFORNIA (US) | 2014-10-29 | — | — | EP | disclosed |