Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839764 | 0.86 | METAP2 (0.52) | IDO1METAP2CYP2C19KIF11PPARA | |
| SCHEMBL8413073 | 0.86 | IDO1 (0.48) | IDO1METAP2CYP2C19ALPIPKM | |
| SCHEMBL4141148 | 0.86 | METAP2 (0.52) | IDO1METAP2CYP2C19KIF11PPARA | |
| SCHEMBL2553802 | 0.86 | METAP2 (0.52) | IDO1METAP2CYP2C19KIF11PPARA | |
| SCHEMBL11880813 | 0.85 | IDO1 (0.45) | IDO1METAP2CYP2C19ALPIPKM | |
| SCHEMBL1927887 | 0.85 | ACE (0.46) | IDO1METAP2CYP2C19ACE | |
| Hydrochloric Acid SCHEMBL3119114 | 0.84 | METAP2 (0.51) | IDO1METAP2KIF11PPARAPPARG | |
| Hydrochloric Acid SCHEMBL4141147 | 0.84 | METAP2 (0.51) | IDO1METAP2KIF11PPARAPPARG | |
| SCHEMBL2238552 | 0.84 | METAP2 (0.60) | IDO1METAP2CYP2C19PPARAPPARG | |
| SCHEMBL7323491 | 0.84 | METAP2 (0.60) | IDO1METAP2CYP2C19PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796546-B1 | Incorporation of unnatural amino acids | SCRIPPS RESEARCH INST (US) | 2017-08-09 | — | — | EP | disclosed |
| EP-2796546-A1 | In vivo incorporation of unnatural amino acids | The Scripps Research Institute (US) | 2014-10-29 | — | — | EP | disclosed |