Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323491 | 1.00 | METAP2 (0.60) | METAP2NPC1RAB9ASMN1; SMN2IDO1 | |
| Hydrochloric Acid SCHEMBL7323488 | 0.98 | METAP2 (0.59) | METAP2NPC1RAB9ASMN1; SMN2IDO1 | |
| Hydrochloric Acid SCHEMBL3366424 | 0.98 | METAP2 (0.59) | METAP2NPC1RAB9ASMN1; SMN2IDO1 | |
| SCHEMBL10519231 | 0.88 | ALDH1A1 (0.49) | METAP2NPC1RAB9ASMN1; SMN2IDO1 | |
| SCHEMBL7317999 | 0.87 | METAP2 (0.47) | METAP2NPC1RAB9ASMN1; SMN2MMP8 | |
| SCHEMBL8413073 | 0.86 | IDO1 (0.48) | METAP2IDO1CYP2C19PPARGPPARA | |
| SCHEMBL1839764 | 0.86 | METAP2 (0.52) | METAP2IDO1CYP2C19PPARGPPARA | |
| SCHEMBL2553802 | 0.86 | METAP2 (0.52) | METAP2IDO1CYP2C19PPARGPPARA | |
| SCHEMBL4141148 | 0.86 | METAP2 (0.52) | METAP2IDO1CYP2C19PPARGPPARA | |
| SCHEMBL28431790 | 0.86 | METAP2 (0.47) | METAP2IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231532-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2020-07-23 | — | — | US | claimed |
| US-20180099923-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2018-04-12 | — | — | US | claimed |
| EP-2536500-B1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2016-12-07 | — | — | EP | claimed |
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-03-21 | — | — | US | claimed |
| EP-2536500-A1 | SUPPORTED METAL CATALYSTS | Johnson Matthey PLC (GB) | 2012-12-26 | — | — | EP | claimed |
| WO-2011101679-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2011-08-25 | — | — | WO | claimed |
| EP-3015488-B1 | PRODUCTION METHOD FOR POLYAMINO ACID | TAKEDA PHARMACEUTICALS CO (JP) | 2024-03-06 | — | — | EP | disclosed |
| US-20200231532-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2020-07-23 | — | — | US | disclosed |
| US-10336864-B2 | Production method for poly(amino acid) | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-07-02 | — | — | US | disclosed |
| US-20180099923-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2018-04-12 | — | — | US | disclosed |
| US-20180044472-A1 | PRODUCTION METHOD FOR POLY(AMINO ACID) | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-02-15 | — | — | US | disclosed |
| US-9815938-B2 | Production method for poly(amino acid) | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-11-14 | — | — | US | disclosed |
| EP-2536500-B1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2016-12-07 | — | — | EP | disclosed |
| EP-0050800-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |
| US-4575503-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1986-03-11 | — | — | US | disclosed |
| EP-0088350-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0119954-A2 | 3-Amino-1-benzazepin-2-one-1-alcanoic acids, process for their preparation, their pharmaceutical preparation as well as their therapeutic use | CIBA-GEIGY AG (CH) | 1984-09-26 | — | — | EP | disclosed |
| US-4431644-A | CARDIOVASCULAR DISORDERS; DIURETICS | SCHERING CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0088350-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1983-09-14 | — | — | EP | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | SOD1, HNMT, SOD3 | METAP2 405/4885NPC1 3027/4885RAB9A 2839/4885 |
| US-20180044472-A1 | PRODUCTION METHOD FOR POLY(AMINO ACID) | PGA5, ENPEP, PARG | METAP2 866/4885NPC1 4601/4885RAB9A 2457/4885 |
| US-20200231532-A1 | Supported Metal Catalysts | SOD1, HNMT, SOD3 | METAP2 405/4885NPC1 3027/4885RAB9A 2839/4885 |
| US-10336864-B2 | Production method for poly(amino acid) | PGA5, ENPEP, PARG | METAP2 866/4885NPC1 4601/4885RAB9A 2457/4885 |
| US-20180099923-A1 | Supported Metal Catalysts | SOD1, HNMT, SOD3 | METAP2 405/4885NPC1 3027/4885RAB9A 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.