Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141148 | 1.00 | METAP2 (0.52) | METAP2KIF11IDO1PPARGPPARA | |
| SCHEMBL2553802 | 1.00 | METAP2 (0.52) | METAP2KIF11IDO1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL3119114 | 0.98 | METAP2 (0.51) | METAP2KIF11IDO1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL4141147 | 0.98 | METAP2 (0.51) | METAP2KIF11IDO1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL2971264 | 0.98 | METAP2 (0.51) | METAP2KIF11IDO1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL2123378 | 0.97 | METAP2 (0.50) | METAP2KIF11IDO1PPARGPPARA | |
| Cyanide SCHEMBL28390031 | 0.96 | METAP2 (0.49) | METAP2KIF11IDO1PPARGPPARA | |
| SCHEMBL2238552 | 0.86 | METAP2 (0.60) | METAP2IDO1PPARGPPARAACE | |
| SCHEMBL31512919 | 0.86 | KIF11 (0.50) | METAP2KIF11IDO1L3MBTL1LTA4H | |
| SCHEMBL7303633 | 0.86 | KIF11 (0.50) | METAP2KIF11L3MBTL1LTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117925570-B | Method for extracting bioactive substances from placenta caprae seu ovis | 蚌埠学院 | 2025-04-22 | — | — | CN | claimed |
| CN-108395523-B | Oxidation helix conformation-reversed isonitrile helical polymer containing thioether side chain and preparation method thereof | 湖北科技学院 | 2020-05-01 | — | — | CN | claimed |
| US-20090234011-A1 | N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS | DAVID PHARMACEUTICALS | 2009-09-17 | — | — | US | claimed |
| EP-1877044-A2 | N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS | Goldstein, Glenn (US) | 2008-01-16 | — | — | EP | claimed |
| WO-2006116353-A2 | N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS | GOLDSTEIN GLENN (US) | 2006-11-02 | — | — | WO | claimed |
| CN-117925570-B | Method for extracting bioactive substances from placenta caprae seu ovis | 蚌埠学院 | 2025-04-22 | — | — | CN | disclosed |
| CN-117925570-B | Method for extracting bioactive substances from placenta caprae seu ovis | 蚌埠学院 | 2025-04-22 | — | — | CN | disclosed |
| CN-117925570-A | Method for extracting bioactive substances from placenta caprae seu ovis | 蚌埠学院 | 2024-04-26 | — | — | CN | disclosed |
| CN-117925570-A | Method for extracting bioactive substances from placenta caprae seu ovis | 蚌埠学院 | 2024-04-26 | — | — | CN | disclosed |
| WO-2022149584-A1 | PEPTIDE | ＡＧＣ株式会社 | 2022-07-14 | — | — | WO | disclosed |
| CN-108395523-B | Oxidation helix conformation-reversed isonitrile helical polymer containing thioether side chain and preparation method thereof | 湖北科技学院 | 2020-05-01 | — | — | CN | disclosed |
| CN-107056730-B | A kind of synthetic method and its application of bupropion hydrochloride sustained release tablets impurity isomers | 浙江普洛家园药业有限公司 | 2019-05-24 | — | — | CN | disclosed |
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997040031-A1 | THIADIAZOLYL(THIO)UREAS USEFUL AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1997-10-30 | — | — | WO | disclosed |
| US-5472698-A | Mixture of (N-acetyl)-L-serine, N-acetylcysteine and alpha-lipoic acid which promotes ceramide production in skin cells | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1995-12-05 | — | — | US | disclosed |
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4931471-A | Amides of paramethoxycinnamic and utilization thereof as solar filters | UNIVERSITE LOUIS PASTEUR (FR) | 1990-06-05 | — | — | US | disclosed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |
| US-4523012-A | INTERMEDIATES FOR PRODUCTION OF D,L-CYSTEINE AND DERIVATIVES | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234011-A1 | N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS | GCLC, NAT1, HHAT | METAP2 1188/4885KIF11 4693/4885IDO1 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.