SCHEMBL16200745

SCHEMBL16200745

Cc1cc(Cn2c(=O)n(Cc3cc(C)c(OC(C)C)c(C)c3)c(=O)n(Cc3cc(C)c(OC(C)C)c(C)c3)c2=O)cc(C)c1OC(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 13/20 0.43
C5AR1 P21730 1/20 0.39
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18800187 0.94 P2RX3 (0.40) P2RX3C5AR1LMNAGAATSHR
SCHEMBL16201822 0.79 C5AR1 (0.41) C5AR1PPARDPPARAKMT2A
SCHEMBL17042665 0.77 C5AR1 (0.38) P2RX3C5AR1PPARDPPARALMNA
SCHEMBL28091694 0.73 PLAU (0.35) PPARA
SCHEMBL17149189 0.73 PPARG (0.34) PPARA
SCHEMBL16201609 0.72 ALDH1A1 (0.38) C5AR1PPARDPPARAMEN1KMT2A
SCHEMBL24703698 0.72 FFAR4 (0.36) PPARAMAPK1HTT
SCHEMBL24420982 0.72 PLAU (0.35) PPARA
SCHEMBL4635049 0.71 C5AR1 (0.44) C5AR1MEN1KMT2A
SCHEMBL17149139 0.70 NOS3 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9642249-B2 Resin composition, prepreg, and substrate employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-05-02 US disclosed
US-9642249-B2 Resin composition, prepreg, and substrate employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-05-02 US disclosed
US-9012572-B2 Polyphenylene ether oligomer and article employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-04-21 US disclosed
US-20140322545-A1 RESIN COMPOSITION, PREPREG, AND SUBSTRATE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-30 US disclosed
US-20140323666-A1 POLYPHENYLENE ETHER OLIGOMER AND ARTICLE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-30 US disclosed