SCHEMBL16200909

SCHEMBL16200909

CNc1ccc2c3c(cccc13)-c1ccccc1-2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.64
USP2 O75604 3/20 0.64
KMT2A Q03164 3/20 0.64
KEAP1 Q14145 2/20 0.64
NFE2L2 Q16236 2/20 0.64
PABPC1 P11940 4/20 0.59
CYP1A2 P05177 3/20 0.53
MAPT P10636 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 2/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
IDO1 P14902 1/20 0.48
MAPK1 P28482 4/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
EGFR P00533 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 4/20 0.44
CASP1 P29466 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28682214 0.83 CYP1A2 (0.65) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL9612793 0.81 MEN1 (0.56) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL28143359 0.79 PABPC1 (0.59) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL6628883 0.79 PABPC1 (0.59) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL30336868 0.77 IDO1 (0.73) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL9778189 0.77 IDO1 (0.73) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL17740736 0.76 MEN1 (0.61) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL9283258 0.75 PABPC1 (0.54) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL12941556 0.73 USP2 (0.49) MEN1USP2KMT2AKEAP1NFE2L2
Bromide SCHEMBL5055196 0.73 PABPC1 (0.53) MEN1USP2KMT2AKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298115-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-03-29 US disclosed
US-9298115-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-03-29 US disclosed
US-20140322637-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed
US-20140322637-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed