Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5055196 | 0.98 | PABPC1 (0.53) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL28682214 | 0.78 | CYP1A2 (0.65) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL6156281 | 0.75 | PABPC1 (0.33) | PABPC1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9455606 | 0.75 | PABPC1 (0.51) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL6156063 | 0.75 | KDM4E (0.32) | PABPC1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6628883 | 0.75 | PABPC1 (0.59) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL16200909 | 0.75 | MEN1 (0.64) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL6155027 | 0.74 | KDM4E (0.34) | CYP1A2KDM4EALDH1A1GAATSHR | |
| SCHEMBL1273874 | 0.74 | KDM4E (0.64) | CYP1A2KDM4EALDH1A1GAATSHR | |
| SCHEMBL4982952 | 0.74 | HSD17B10 (0.45) | PABPC1CYP1A2KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995020950-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-08-10 | — | — | WO | disclosed |