Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803898 | 0.91 | MAPT (0.50) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL11016312 | 0.85 | MEN1 (0.63) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL2222503 | 0.81 | MEN1 (0.56) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL5273122 | 0.80 | MAPT (0.52) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL6941009 | 0.79 | MEN1 (0.57) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7369725 | 0.78 | MAPT (0.68) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7697932 | 0.78 | MAPT (0.51) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL13964086 | 0.77 | NPC1 (0.62) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4034758 | 0.77 | NPC1 (0.62) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL986085 | 0.77 | MEN1 (0.52) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957214-A | Preparation method of chlorantraniliprole intermediate | 九江善水科技股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-7582636-B2 | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor | WYETH (US) | 2009-09-01 | — | — | US | claimed |
| US-20060270848-A1 | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-11-30 | — | — | US | claimed |
| EP-4745134-A1 | PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| CN-111909082-B | Pyridine hydrazone derivatives, and preparation method and application thereof | 湖南大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-114957214-A | Preparation method of chlorantraniliprole intermediate | 九江善水科技股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114957214-A | Preparation method of chlorantraniliprole intermediate | 九江善水科技股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11173151-B2 | Substituted triazole derivatives and uses thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2021-11-16 | — | — | US | disclosed |
| CN-105315199-B | N-pyridine aryloxy phenoxy carboxylic acid derivative and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-111909082-A | Pyridine hydrazone derivatives, and preparation method and application thereof | 湖南大学 | 2020-11-10 | — | — | CN | disclosed |
| EP-3089966-B1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | ESTRYX PHARMA LTD (GB) | 2020-10-21 | — | — | EP | disclosed |
| EP-0559843-B1 | SUBSTITUTED N-HETEROBICYCLIC HERBICIDES | DU PONT (US) | 1994-09-14 | — | — | EP | disclosed |
| WO-1994007910-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| EP-0559843-A1 | SUBSTITUTED N-HETEROBICYCLIC HERBICIDES. | DU PONT (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009578-A1 | SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5110347-A | Pre- and postemergence; quinoxaline derivatives | E. I DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0159112-A1 | Process for the preparation of diaminopyridines | ELI LILLY AND COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4165238-A | DIFFUSION TRANSFER, BALLASTED, METALLIZED | EASTMAN KODAK COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4147544-A | Photographic products and processes employing novel nondiffusible pyridylazonaphthol dye-releasing compounds | EASTMAN KODAK COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-4121036-A | 3-Amino-2-Hydrazinopyridine derivatives | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270848-A1 | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of gonadotropin releasing hormone receptor | GNRHR, PRLHR, FSHR | MAPT 3908/4885RAB9A 3912/4885NPC1 3818/4885 |
| US-11173151-B2 | Substituted triazole derivatives and uses thereof | GLS, TNNI3, CYP11B2 | MAPT 4107/4885RAB9A 2607/4885NPC1 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.