Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GALR2 | O43603 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941009 | 0.86 | MEN1 (0.57) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL11016312 | 0.85 | MEN1 (0.63) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL1620133 | 0.81 | MAPT (0.57) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL986085 | 0.81 | MEN1 (0.52) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL12890441 | 0.81 | KMT2A (0.52) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL4034758 | 0.81 | NPC1 (0.62) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL7854150 | 0.80 | TDP1 (0.47) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL9687003 | 0.80 | LMNA (0.54) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL4546442 | 0.80 | MEN1 (0.51) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL7697932 | 0.78 | MAPT (0.51) | MEN1KMT2AL3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570688-B | 2,5-diaminomethyl pyrazine compounds, its pharmaceutical composition, preparation method and purposes | 中国科学院上海药物研究所 | 2016-06-08 | — | — | CN | claimed |
| CN-103570688-A | 2,5-diaminomethylpyrazine compounds, drug compositions, preparation method and use thereof | SHANGHAI INST MATERIA MEDICA | 2014-02-12 | — | — | CN | claimed |
| US-11600791-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-03-07 | — | — | US | disclosed |
| EP-3936512-A1 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | Universal Display Corporation (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3936512-A1 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | Universal Display Corporation (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3424935-B1 | IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORP (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-3424935-B1 | IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORP (US) | 2021-08-11 | — | — | EP | disclosed |
| US-20210050530-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
| US-20210050530-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
| US-10873038-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-12-22 | — | — | US | disclosed |
| US-10873038-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-12-22 | — | — | US | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| CN-1118781-A | Heterocyclic compound with activity against diabetes and preparation and application of same | MITSUTAKA CO LTD (JP) | 1996-03-20 | — | — | CN | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0283162-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-08-11 | — | — | EP | disclosed |
| US-4902686-A | Tricyclic heterocyclic compounds and their use in treating benzodiazepin receptor-related ailments | A/S FERROSAN (DK) | 1990-02-20 | — | — | US | disclosed |
| US-4873244-A | AILMENTS ASSOCIATED WITH BENZODIAZEPINE RECEPTORS | A/S FERROSAN (DK) | 1989-10-10 | — | — | US | disclosed |
| EP-0283162-A2 | Heterocyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-09-21 | — | — | EP | disclosed |
| US-4520196-A | α-Mercaptophenylacetic acid derivatives of imidazole-containing compounds and analogues thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210050530-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | NUDC, NCL, NDC1 | MEN1 2130/4885KMT2A 3120/4885L3MBTL1 1096/4885 |
| US-10873038-B2 | Organic electroluminescent materials and devices | NUDC, NCL, NDC1 | MEN1 2130/4885KMT2A 3120/4885L3MBTL1 1096/4885 |
| US-11600791-B2 | Organic electroluminescent materials and devices | NUDC, NCL, NDC1 | MEN1 2130/4885KMT2A 3120/4885L3MBTL1 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.