SCHEMBL162015

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL69256	0.79	CA1 (0.47)	MAPTHTTKMT2ACA12CA1
	SCHEMBL14372978	0.79	MAPT (0.56)	MAPTHTTKMT2AMEN1CYP1A2
	SCHEMBL23682836	0.79	MAPT (0.47)	MAPTHTTKMT2AMEN1CYP1A2
	SCHEMBL162071	0.79	CYP2C9 (0.33)	MAPTCYP2C19CA12CA1CA2
	SCHEMBL161855	0.79	CA12 (0.43)	KMT2AMEN1CYP1A2CYP2C19CA12
	SCHEMBL162633	0.79	NPC1 (0.38)	MAPTKMT2AMEN1CYP1A2CYP2C19
	SCHEMBL16693616	0.78	HTT (0.43)	MAPTHTTKMT2AMEN1CYP1A2
	SCHEMBL22833444	0.78	CHRNA4 (0.44)	MAPTHTTKMT2AMEN1CYP1A2
	SCHEMBL26018323	0.78	MAPT (0.42)	MAPTHTTKMT2AMEN1CYP1A2
	SCHEMBL1529732	0.78	CHRNB2 (0.44)	MAPTHTTKMT2AMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.