Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MLYCD | O95822 | 2/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25942822 | 0.91 | MLYCD (0.59) | NPC1RAB9AMLYCDTRPM8SMN1; SMN2 | |
| SCHEMBL5696786 | 0.82 | MLYCD (0.69) | NPC1RAB9AMLYCDSMN1; SMN2MEN1 | |
| SCHEMBL9877627 | 0.81 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7513376 | 0.80 | TRPM8 (0.58) | NPC1RAB9ATRPM8SMN1; SMN2MAPT | |
| SCHEMBL25942908 | 0.80 | MLYCD (0.59) | NPC1RAB9AMLYCDSMN1; SMN2MAPT | |
| SCHEMBL3060224 | 0.79 | MLYCD (0.50) | NPC1RAB9AMLYCDCYP2C19MEN1 | |
| SCHEMBL1019065 | 0.78 | MLYCD (0.65) | NPC1RAB9AMLYCDSMN1; SMN2MEN1 | |
| SCHEMBL16197861 | 0.78 | CYP2D6 (0.66) | NPC1RAB9AMLYCDMAPTCYP1A2 | |
| SCHEMBL11803183 | 0.77 | MAPT (0.78) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL9327118 | 0.76 | MLYCD (0.55) | NPC1RAB9AMLYCDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014175832-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-30 | — | — | WO | disclosed |