SCHEMBL16201615

SCHEMBL16201615

Cc1ccc(Oc2ccc(C(C)(c3ccc(Oc4ccc(N5C(=O)C6CC7C(=O)N(C)C(=O)C7CC6C5=O)cc4)cc3)C(F)(F)F)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
NPBWR1 P48145 1/20 0.35
MCHR1 Q99705 1/20 0.35
ACHE P22303 1/20 0.35
TP53 P04637 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13472599 0.89 LMNA (0.43) LMNAALDH1A1POLBSMN1; SMN2ACHE
SCHEMBL9911156 0.87 LMNA (0.49) LMNAALDH1A1POLBSMN1; SMN2ACHE
SCHEMBL13624488 0.83 LMNA (0.46) LMNAALDH1A1POLBSMN1; SMN2ACHE
SCHEMBL17721622 0.82 LMNA (0.45) LMNAALDH1A1POLBACHETP53
SCHEMBL14342131 0.82 LMNA (0.46) LMNAALDH1A1POLBSMN1; SMN2ACHE
SCHEMBL19399222 0.81 LMNA (0.48) LMNAALDH1A1POLBACHETP53
SCHEMBL16201610 0.81 LMNA (0.48) LMNAALDH1A1POLBACHETP53
SCHEMBL13472598 0.79 LMNA (0.56) LMNAALDH1A1POLBACHETP53
SCHEMBL10028907 0.79 LMNA (0.37) LMNAALDH1A1POLBSMN1; SMN2ACHE
SCHEMBL13773285 0.77 TP53 (0.42) LMNAALDH1A1SMN1; SMN2TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9073297-B2 Method for manufacturing transparent, heat-resistant gas-barrier film MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-07-07 US disclosed
US-20140322444-A1 METHOD FOR MANUFACTURING TRANSPARENT, HEAT-RESISTANT GAS-BARRIER FILM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-10-30 US disclosed