Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 4/20 | 0.34 |
| ▸ | PRKCG | P05129 | 3/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | PRKCH | P24723 | 2/20 | 0.34 |
| ▸ | PRKCI | P41743 | 2/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | SI | P14410 | 2/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16201633 | 0.78 | TLR8 (0.38) | CYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL16201635 | 0.74 | — | — | |
| SCHEMBL16201627 | 0.73 | CHRNA7 (0.37) | PRKCBPRKCGPRKCAPRKCEPRKCD | |
| SCHEMBL7376810 | 0.73 | BRD4 (0.40) | PRKCBPRKCGPRKCAPRKCEPRKCD | |
| SCHEMBL16201631 | 0.73 | MTNR1A (0.45) | GAACYP1A2CYP2D6KDM4EALDH1A1 | |
| SCHEMBL16201625 | 0.70 | LMNA (0.31) | PRKCBPRKCGPRKCAPRKCEPRKCD | |
| SCHEMBL16201659 | 0.68 | POLB (0.40) | PRKCBPRKCGPRKCAPRKCEPRKCD | |
| SCHEMBL16201626 | 0.67 | TSHR (0.44) | PRKCBPRKCGPRKCAPRKCEPRKCD | |
| SCHEMBL16201666 | 0.66 | CYP1A2 (0.43) | GAACYP1A2CYP2D6KDM4EALDH1A1 | |
| SCHEMBL17616023 | 0.65 | GPR3 (0.52) | GAAMGAMSIMGAM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345905-B2 | Heterocyclic amides compounds which are HDAC6 inhibitors and used as anti-tumoral agents | NANJING ALLGEN PHARMA CO. LTD. (CN) | 2016-05-24 | — | — | US | disclosed |
| US-20140322229-A1 | HETEROCYCLIC AMIDES COMPOUNDS WHICH ARE HDAC6 INHIBITORS AND USED AS ANTI-TUMORAL AGENTS | BETA PHARMA CANADA INC. (CA) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322229-A1 | HETEROCYCLIC AMIDES COMPOUNDS WHICH ARE HDAC6 INHIBITORS AND USED AS ANTI-TUMORAL AGENTS | HDAC6, HDAC1, HDAC7 | PRKCB 3163/4885PRKCG 3518/4885PRKCA 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.