SCHEMBL16202061

SCHEMBL16202061

C=CCO/N=C(\C)c1ccc(C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.54
LMNA P02545 4/20 0.46
PTBP1 P26599 1/20 0.46
L3MBTL1 Q9Y468 4/20 0.44
MAPK1 P28482 2/20 0.44
HTT P42858 1/20 0.44
CYP1A2 P05177 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
S1PR1 P21453 1/20 0.40
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
MAPT P10636 3/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13215248 0.85 SMN1; SMN2 (0.53) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL6269349 0.85 SMN1; SMN2 (0.53) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL3030362 0.82 SMN1; SMN2 (0.51) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL13215229 0.82 SMN1; SMN2 (0.51) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL3030363 0.82 SMN1; SMN2 (0.51) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL16202013 0.82 SMN1; SMN2 (0.48) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL13683674 0.82 SMN1; SMN2 (0.52) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL5197523 0.81 SMN1; SMN2 (0.50) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL5197529 0.81 SMN1; SMN2 (0.50) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1
SCHEMBL17218743 0.80 SMN1; SMN2 (0.46) SMN1; SMN2LMNAPTBP1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-26 US disclosed
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi BASF SE (DE) 2016-05-26 US disclosed
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-05 US disclosed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US disclosed
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI SNX1, DPM1, SNU13 SMN1; SMN2 2653/4885LMNA 4479/4885PTBP1 2494/4885
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI DPM1, CROCC, SNX1 SMN1; SMN2 3486/4885LMNA 4670/4885PTBP1 2745/4885
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi DPM1, CROCC, SNX1 SMN1; SMN2 3486/4885LMNA 4670/4885PTBP1 2745/4885
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB SMN1; SMN2 2724/4885LMNA 3613/4885PTBP1 2774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.