Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 14/20 | 0.67 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.67 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.54 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | GPR183 | P32249 | 1/20 | 0.54 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904106 | 0.90 | S1PR1 (0.64) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL589369 | 0.85 | S1PR1 (0.58) | S1PR1S1PR3 | |
| SCHEMBL565320 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL14555240 | 0.84 | S1PR1 (0.73) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL16202260 | 0.81 | S1PR1 (0.55) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL16590221 | 0.80 | S1PR1 (0.48) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL1687946 | 0.80 | S1PR1 (0.53) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL1687940 | 0.80 | S1PR1 (0.53) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL1687904 | 0.80 | S1PR1 (0.53) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL14555248 | 0.80 | S1PR1 (0.53) | S1PR1S1PR3TNNC1SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323501-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-10-30 | — | — | US | disclosed |
| US-20140323501-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323501-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | AADAT, HPGDS, HLA-DRB1 | S1PR1 1288/4885S1PR3 1875/4885TNNC1 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.