Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 7/20 | 0.64 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.64 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.64 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.64 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.64 |
| ▸ | SRC | P12931 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.63 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.63 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.63 |
| ▸ | LDHA | P00338 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | FBP1 | P09467 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.63 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29995120 | 0.93 | P2RY1 (0.74) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL13853911 | 0.93 | P2RY1 (0.74) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL20277564 | 0.90 | P2RX3 (0.62) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL12932262 | 0.90 | P2RY1 (0.79) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL13995541 | 0.89 | DNPH1 (0.77) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL10295499 | 0.89 | P2RY1 (0.71) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL10295496 | 0.88 | P2RY1 (0.67) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL14853898 | 0.86 | P2RY1 (0.73) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL14853916 | 0.84 | P2RY1 (0.64) | P2RX3P2RX2P2RY1P2RY2P2RX1 | |
| SCHEMBL23711717 | 0.83 | P2RX3 (0.74) | P2RX3P2RX2P2RY1P2RY2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323354-A1 | Chemically Modified Ligase Cofactors, Donors and Acceptors | TRILINK BIOTECHNOLOGIES, INC. (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140323354-A1 | Chemically Modified Ligase Cofactors, Donors and Acceptors | TRILINK BIOTECHNOLOGIES, INC. (US) | 2014-10-30 | — | — | US | disclosed |