SCHEMBL1620372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1620818	0.78	ALDH1A1 (0.44)	CYP3A4MAPTCYP2C9CYP1A2TUBB4A
	SCHEMBL3212159	0.77	ALOX15 (0.44)	ALOX15ALOX12CA1CA2CA4
	SCHEMBL1620237	0.75	CYP3A4 (0.40)	ALOX15ALOX12CYP3A4MAPTCYP2C9
	SCHEMBL1620100	0.75	ALOX15 (0.37)	ALOX15ALOX12HTR2AGAACYP1A2
	SCHEMBL14154475	0.73	PTGS2 (0.50)	ALOX15ALOX12CA1CA2CA4
	SCHEMBL5304107	0.73	HTR2A (0.57)	CYP3A4HTR2ACYP1A2
	SCHEMBL5304110	0.73	HTR2A (0.57)	CYP3A4HTR2ACYP1A2
	SCHEMBL2130516	0.72	KDM4E (0.38)	—
	SCHEMBL6719608	0.72	ALOX15 (0.43)	ALOX15ALOX12CA1CA2CA4
	SCHEMBL5549042	0.72	ALOX15 (0.47)	ALOX15ALOX12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.