SCHEMBL1620437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12261791	0.80	SMN1; SMN2 (0.61)	SMN1; SMN2HTTCYP2D6CYP1A2CYP2C19
	SCHEMBL12261734	0.78	SMN1; SMN2 (0.59)	SMN1; SMN2HTTCYP2D6CYP1A2CYP2C19
	SCHEMBL16404334	0.78	CYP2D6 (0.87)	SMN1; SMN2HTTCYP2D6CYP1A2CYP2C19
	SCHEMBL5526236	0.78	SMN1; SMN2 (0.59)	NUDT1SMN1; SMN2HTTCYP2D6CYP1A2
	SCHEMBL25247772	0.78	NUDT1 (0.61)	NUDT1SMN1; SMN2HTTCYP2D6CYP1A2
	SCHEMBL25286799	0.78	NUDT1 (0.61)	NUDT1SMN1; SMN2HTTCYP2D6CYP1A2
	SCHEMBL4197866	0.78	NUDT1 (0.61)	NUDT1SMN1; SMN2CYP1A2TSHRMAPK1
	SCHEMBL1084629	0.78	EGFR (0.59)	SMN1; SMN2HTTCYP2D6CYP1A2CYP2C19
	SCHEMBL13458340	0.78	SMN1; SMN2 (0.59)	SMN1; SMN2HTTCYP2D6CYP1A2CYP2C19
	SCHEMBL1083866	0.78	CYP2D6 (0.81)	SMN1; SMN2CYP2D6CYP1A2CYP2C19CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.