SCHEMBL1620439

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8208619	0.96	KDM4E (0.46)	KDM4EALDH1A1CA1CA2CA12
	SCHEMBL19358495	0.83	L3MBTL1 (0.51)	KDM4EALDH1A1POLBGAAL3MBTL1
	SCHEMBL18985150	0.82	CA1 (0.58)	KDM4EALDH1A1CA1CA2CA12
	SCHEMBL1620440	0.77	CYP2C19 (0.54)	ALDH1A1CA1CA2CA12CA7
	SCHEMBL147169	0.76	CA1 (0.71)	KDM4EALDH1A1CA1CA2CA12
	SCHEMBL1791405	0.76	CA1 (0.50)	KDM4EALDH1A1CA1CA2CA12
	SCHEMBL475746	0.74	CA1 (0.61)	KDM4EALDH1A1CA1CA2CA12
	SCHEMBL18304558	0.74	KDM4E (0.44)	KDM4EALDH1A1CA1CA2CA12
	SCHEMBL15154213	0.73	KMT2A (0.38)	KDM4EALDH1A1LMNAPOLBGAA
	SCHEMBL18428478	0.73	ALDH1A1 (0.33)	ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.