Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620439 | 0.96 | KDM4E (0.46) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL19358495 | 0.83 | L3MBTL1 (0.51) | KDM4EALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL18985150 | 0.82 | CA1 (0.58) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL18428478 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1107694 | 0.76 | CA1 (0.50) | KDM4EALDH1A1CA1CA2CA12 | |
| Methyl 3,5-Dimethoxybenzoate SCHEMBL204865 | 0.74 | CA1 (0.61) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL23906958 | 0.74 | ALDH1A1 (0.52) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL17203693 | 0.74 | ALDH1A1 (0.52) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL6625609 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1CA1CA2CA12 | |
| SCHEMBL1620440 | 0.73 | CYP2C19 (0.54) | ALDH1A1CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069238-A | FOR USE AS CHEMICAL INTERMEDIATES FOR THE EFFICIENT, HIGH YIELD PREPARATION OF PAPULACANDIN COMPOUNDS AND ANALOGS, WHICH ARE ANTIBIOTICS/FUNGICIDES | ELI LILLY AND COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0997472-A2 | Spirocyclic C-glycosides | ELI LILLY AND COMPANY (US) | 2000-05-03 | — | — | EP | disclosed |