Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 1.00 |
| ▸ | AKR1C3 | P42330 | 4/20 | 1.00 |
| ▸ | CNR2 | P34972 | 1/20 | 1.00 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.84 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.82 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | PTGES | O14684 | 1/20 | 0.82 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.82 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.82 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.82 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | ALB | P02768 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.82 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.82 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086813 | 1.00 | PTGS2 (1.00) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL11092811 | 0.94 | PTGS2 (0.88) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL8978311 | 0.93 | PTGS2 (0.86) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL14031839 | 0.92 | PTGS2 (0.84) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL28817657 | 0.92 | PTGS2 (0.84) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL4549122 | 0.92 | PTGS2 (1.00) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL16656482 | 0.91 | AKR1C3 (1.00) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL12988768 | 0.91 | PTGS2 (0.86) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL29855593 | 0.91 | PTGS2 (0.86) | PTGS2AKR1C3CNR2AKR1C2PTGS1 | |
| SCHEMBL10788764 | 0.91 | PTGS2 (0.83) | PTGS2AKR1C3CNR2AKR1C2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12065422-B2 | Reagents and process for direct C—H functionalization | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-08-20 | — | — | US | disclosed |
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-07-20 | — | — | US | disclosed |
| US-11608322-B2 | Reagents and process for direct C—H functionalization | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | CFH, DOHH, CTSH | PTGS2 3723/4885AKR1C3 598/4885CNR2 1766/4885 |
| US-11608322-B2 | Reagents and process for direct C—H functionalization | CFH, DOHH, CTSH | PTGS2 3850/4885AKR1C3 756/4885CNR2 1883/4885 |
| US-12065422-B2 | Reagents and process for direct C—H functionalization | CFH, DOHH, CTSH | PTGS2 3850/4885AKR1C3 756/4885CNR2 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.