Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607415 | 1.00 | HRH3 (0.44) | HRH3CSF1RMAPK1AKT1MAPK8 | |
| SCHEMBL15607210 | 0.87 | HRH3 (0.41) | HRH3CSF1RMAPK1AKT1MAPK8 | |
| SCHEMBL16205115 | 0.87 | HRH3 (0.41) | HRH3CSF1RMAPK1AKT1MAPK8 | |
| SCHEMBL15607447 | 0.86 | HRH3 (0.41) | HRH3KCNH2FKBP1ACYP3A4MAPK14 | |
| SCHEMBL16205057 | 0.86 | HRH3 (0.41) | HRH3KCNH2FKBP1ACYP3A4MAPK14 | |
| SCHEMBL15566352 | 0.85 | MAPT (0.42) | HRH3MEN1KMT2AMAPT | |
| SCHEMBL618258 | 0.82 | HCRTR2 (0.40) | HRH3MAPT | |
| SCHEMBL620851 | 0.82 | HCRTR2 (0.40) | HRH3MAPT | |
| SCHEMBL618257 | 0.82 | HCRTR2 (0.40) | HRH3MAPT | |
| SCHEMBL618602 | 0.81 | HRH3 (0.39) | HRH3MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3593648-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| CN-104603132-B | Sweet taste modifier | 弗门尼舍公司 | 2020-02-21 | — | — | CN | disclosed |
| US-9745293-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9687015-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2016-11-17 | — | — | US | disclosed |
| US-9420814-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| US-9138013-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC | 2015-01-29 | — | — | US | disclosed |
| US-8877922-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3079/4885CSF1R 2261/4885MAPK1 4306/4885 |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3079/4885CSF1R 2261/4885MAPK1 4306/4885 |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3166/4885CSF1R 2395/4885MAPK1 4326/4885 |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3166/4885CSF1R 2395/4885MAPK1 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.