Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607210 | 1.00 | HRH3 (0.41) | HRH3KCNH2ALDH1A1PAX8FKBP1A | |
| SCHEMBL15607415 | 0.87 | HRH3 (0.44) | HRH3KCNH2FKBP1AMEN1KMT2A | |
| SCHEMBL16204992 | 0.87 | HRH3 (0.44) | HRH3KCNH2FKBP1AMEN1KMT2A | |
| SCHEMBL15567768 | 0.87 | ALDH1A1 (0.39) | HRH3ALDH1A1KMT2A | |
| SCHEMBL28362245 | 0.84 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL19034771 | 0.83 | ALDH1A1 (0.32) | ALDH1A1PAX8CSF1RMAPK1AKT1 | |
| SCHEMBL15607447 | 0.82 | HRH3 (0.41) | HRH3KCNH2ALDH1A1PAX8FKBP1A | |
| SCHEMBL16205057 | 0.82 | HRH3 (0.41) | HRH3KCNH2ALDH1A1PAX8FKBP1A | |
| SCHEMBL18224085 | 0.79 | F2RL3 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15607442 | 0.79 | F2RL3 (0.40) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3593648-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-3593648-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| CN-104603132-B | Sweet taste modifier | 弗门尼舍公司 | 2020-02-21 | — | — | CN | disclosed |
| US-9745293-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9687015-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2016-11-17 | — | — | US | disclosed |
| US-9420814-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| US-9138013-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC | 2015-01-29 | — | — | US | disclosed |
| US-8877922-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3079/4885KCNH2 1337/4885ALDH1A1 613/4885 |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3079/4885KCNH2 1337/4885ALDH1A1 613/4885 |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3166/4885KCNH2 1249/4885ALDH1A1 445/4885 |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HRH3 3166/4885KCNH2 1249/4885ALDH1A1 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.