Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28207000 | 0.89 | RIPK1 (0.43) | KMT2AMEN1TSHRHTTRIPK1 | |
| SCHEMBL580929 | 0.84 | AKR1C3 (0.51) | RIPK1AKR1C3AKR1C1L3MBTL1POLB | |
| SCHEMBL16205310 | 0.81 | KMT2A (0.44) | KMT2AMEN1POLB | |
| SCHEMBL28194309 | 0.81 | RIPK1 (0.74) | KMT2ARIPK1 | |
| SCHEMBL582155 | 0.81 | RIPK1 (0.47) | KMT2AMEN1RIPK1AKR1C3AKR1C1 | |
| SCHEMBL12964250 | 0.80 | RIPK1 (0.64) | KMT2AMEN1TSHRHTTRIPK1 | |
| Hydrochloric Acid SCHEMBL27412469 | 0.78 | RIPK1 (0.62) | KMT2AMEN1TSHRHTTRIPK1 | |
| SCHEMBL27831765 | 0.78 | RIPK1 (0.58) | KMT2AMEN1TSHRHTTRIPK1 | |
| SCHEMBL29943144 | 0.78 | CHRNB2 (0.53) | RIPK1AKR1C3AKR1C1L3MBTL1NOTUM | |
| SCHEMBL24366348 | 0.77 | RIPK1 (0.50) | RIPK1AKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847765-A | The piperidine derivative of 1,4 substitutions | 赛福伦公司 | 2018-03-27 | — | — | CN | disclosed |
| US-8877968-B2 | Melanocortin receptor modulators, process for preparing them and use there in human medicine and cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-11-04 | — | — | US | disclosed |