Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964250 | 0.95 | RIPK1 (0.64) | RIPK1MEN1KMT2ATSHRHTT | |
| Hydrochloric Acid SCHEMBL27412469 | 0.94 | RIPK1 (0.62) | RIPK1MEN1KMT2ATSHRHTT | |
| SCHEMBL28046212 | 0.87 | HSP90AA1 (0.44) | RIPK1MEN1KMT2ATSHRHTT | |
| SCHEMBL28112744 | 0.84 | RIPK1 (0.57) | RIPK1HSD11B1EPHX2PRMT5WDR77 | |
| SCHEMBL28005101 | 0.84 | ALDH1A1 (0.56) | RIPK1HSD11B1PPIDEPHX2BACE1 | |
| SCHEMBL20905497 | 0.84 | RIPK1 (0.61) | RIPK1MEN1KMT2AHSD11B1PPID | |
| SCHEMBL9336982 | 0.83 | RIPK1 (0.63) | RIPK1HSD11B1EPHX2PRMT5WDR77 | |
| SCHEMBL8303313 | 0.82 | TMEM97 (0.58) | RIPK1HSD11B1PRMT5WDR77TMEM97 | |
| SCHEMBL14569542 | 0.82 | RIPK1 (0.49) | RIPK1MEN1KMT2ATSHRHTT | |
| SCHEMBL26984487 | 0.82 | TMEM97 (0.58) | RIPK1HSD11B1PRMT5WDR77TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712628-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-15 | — | — | CN | claimed |
| CN-102712628-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | claimed |
| CN-104672214-A | Compound with ALK inhibition activity as well as preparation method and use of compound | SHANGHAI HANSOH BIOMEDICAL CO LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-102712628-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-102083920-B | Antifouling compounds and use thereof | UNIV SINGAPORE | 2014-05-14 | — | — | CN | disclosed |
| CN-102712628-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | disclosed |
| CN-102083920-A | Antifouling compounds and use thereof | UNIV SINGAPORE | 2011-06-01 | — | — | CN | disclosed |