Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029426 | 0.77 | ALDH1A1 (0.33) | POLBSMN1; SMN2 | |
| SCHEMBL28144633 | 0.74 | HRH3 (0.31) | — | |
| SCHEMBL329331 | 0.73 | GBA1 (0.32) | POLBTSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL5302977 | 0.71 | RAB9A (0.38) | TSHRSMN1; SMN2SIGMAR1HPGD | |
| SCHEMBL16206234 | 0.71 | NR1I2 (0.43) | POLBTSHRSMN1; SMN2NR1I2SIGMAR1 | |
| SCHEMBL5287172 | 0.69 | GBA1 (0.31) | — | |
| SCHEMBL5286518 | 0.69 | EBP (0.36) | POLBTSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL21065371 | 0.69 | KDM4E (0.31) | — | |
| SCHEMBL5282342 | 0.68 | EBP (0.39) | POLBTSHRSIGMAR1 | |
| SCHEMBL5290943 | 0.68 | EBP (0.39) | POLBTSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172885-A1 | GROUP 9 TRANSITION METAL CATALYSTS AND PROCESS FOR USE OF SAME | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2014-10-30 | — | — | WO | disclosed |