Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28144633 | 0.87 | HRH3 (0.31) | ALDH1A1KDM4EHRH3 | |
| SCHEMBL21580600 | 0.80 | RAPGEF4 (0.34) | ALDH1A1KDM4ERAPGEF4 | |
| SCHEMBL7760842 | 0.79 | ALDH1A1 (0.33) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL17532970 | 0.79 | ALDH1A1 (0.32) | ALDH1A1KDM4ERAPGEF4POLBMAPT | |
| SCHEMBL24613025 | 0.78 | HRH3 (0.33) | HRH3MAPT | |
| SCHEMBL12852201 | 0.77 | KDM4E (0.32) | ALDH1A1KDM4ERAPGEF4 | |
| SCHEMBL12852204 | 0.77 | KDM4E (0.32) | ALDH1A1KDM4ERAPGEF4 | |
| SCHEMBL12852210 | 0.77 | KDM4E (0.32) | ALDH1A1KDM4ERAPGEF4 | |
| SCHEMBL16206237 | 0.77 | POLB (0.34) | POLBSMN1; SMN2 | |
| SCHEMBL16388937 | 0.77 | ALDH1A1 (0.35) | ALDH1A1KDM4EHRH3POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11801528-B2 | Carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2023-10-31 | — | — | US | disclosed |
| US-11713361-B2 | Hydrogenation catalyst compositions and their use for hydrogenation of nitrile rubber | ARLANXEO DEUTSCHLAND GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11673130-B2 | Catalyst system containing a metathesis catalyst and at least one phenolic compound and a process for metathesis of nitrile-butadiene rubber (NBR) using the catalyst system | ARLANXEO DEUTSCHLAND GMBH (DE) | 2023-06-13 | — | — | US | disclosed |
| US-11383266-B2 | Carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2022-07-12 | — | — | US | disclosed |
| WO-2019201730-A1 | HYDROGENATION CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER | ARLANXEO DEUTSCHLAND GMBH (DE) | 2019-10-24 | — | — | WO | disclosed |
| US-20180223005-A1 | CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-10011664-B2 | Functionalized nitrile rubbers and the production thereof | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-07-03 | — | — | US | disclosed |
| US-10000584-B2 | Hydrogenation of nitrile rubber | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-9920086-B2 | Ruthenium-based complexes, their preparation and use as catalysts | ARLANXEO DE GMBH (DE) | 2018-03-20 | — | — | US | disclosed |
| US-9828401-B2 | Ruthenium-based complex catalysts | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-7662889-B2 | Process for the metathetic degradation of nitrile rubbers | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-16 | — | — | US | disclosed |
| US-20090076226-A1 | CATALYSTS FOR METATHESIS REACTIONS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090076227-A1 | PROCESS FOR THE METATHETIC DEGRADATION OF NITRILE RUBBER | LANXESS DEUTSCHLAND GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090069516-A1 | CATALYST SYSTEMS AND THEIR USE FOR METATHESIS REACTIONS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090054597-A1 | Metathesis of Nitrile Rubbers In the Presence of Transition Metal Complex Catalysts | LANXESS DEUTSCHLAND GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| US-7470750-B2 | Method for the degradation of nitrile rubber by metathesis in the presence of ruthenium- or osmium-based catalysts | LANXESS DEUTSCHLAND GMBH (DE) | 2008-12-30 | — | — | US | disclosed |
| US-20080076881-A1 | Process for the metathetic degradation of nitrile rubbers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2008-03-27 | — | — | US | disclosed |
| US-20080064822-A1 | Process for degrading nitrile rubbers in the presence of catalysts having an increased activity | ARLANXEO DEUTSCHLAND GMBH (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20070208206-A1 | Novel catalyst systems and a process for reacting chemical compounds in the presence of said catalyst systems | LANXESS DEUTSCHLAND GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| US-20070049700-A1 | Method for the degradation of nitrile rubber by metathesis in the presence of ruthenium- or osmium-based catalysts | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076226-A1 | CATALYSTS FOR METATHESIS REACTIONS | MCM4, MNS1, TERT | ALDH1A1 2759/4885KDM4E 4160/4885RAPGEF4 1305/4885 |
| US-20070208206-A1 | Novel catalyst systems and a process for reacting chemical compounds in the presence of said catalyst systems | NBAS, NNMT, CAT | ALDH1A1 2504/4885KDM4E 3404/4885RAPGEF4 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.