SCHEMBL162069

SCHEMBL162069

Cc1cc(C)c(-c2c3nc(c(-c4ccc(N)cc4)c4ccc([nH]4)c(-c4c(C)cc(C)cc4C)c4nc(cc5ccc2[nH]5)C=C4)C=C3)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.53
▸ STAT1 P42224 1/20 0.53
▸ TOP1 P11387 4/20 0.51
▸ TERT O14746 5/20 0.40
▸ ABCG2 Q9UNQ0 1/20 0.38
▸ CYCS P99999 3/20 0.38
▸ ENPP2 Q13822 1/20 0.38
▸ RPS6KA3 P51812 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93007 0.92 STAT3 (0.56) STAT3STAT1TOP1TERTABCG2
SCHEMBL16882370 0.91 STAT3 (0.44) STAT3STAT1TOP1TERTABCG2
SCHEMBL10100940 0.89 STAT3 (0.64) STAT3STAT1TOP1TERTABCG2
SCHEMBL30372046 0.89 STAT3 (0.64) STAT3STAT1TOP1TERTABCG2
SCHEMBL1344998 0.89 TOP1 (0.62) TOP1TERTABCG2CYCSENPP2
SCHEMBL13970977 0.89 STAT3 (0.69) STAT3STAT1TOP1TERTABCG2
SCHEMBL6048211 0.89 STAT3 (0.69) STAT3STAT1TOP1TERTABCG2
SCHEMBL78903 0.87 STAT3 (0.56) STAT3STAT1TOP1TERTABCG2
SCHEMBL26285585 0.86 STAT3 (0.55) STAT3STAT1TOP1TERTABCG2
SCHEMBL78729 0.86 STAT3 (0.50) STAT3STAT1TOP1TERTABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9076972-B2 Soluble porphyrin polymers ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2015-07-07 — — US disclosed
US-8926821-B2 Use of diazonium salts for the formation of thick layers on at least one surface of a substrate COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-01-06 — — US disclosed
US-8669359-B2 Electrically conducting porphyrin and porphyrin-fullerene electropolymers ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-03-11 — — US disclosed
US-8669359-B2 Electrically conducting porphyrin and porphyrin-fullerene electropolymers ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-03-11 — — US disclosed
US-8669359-B2 Electrically conducting porphyrin and porphyrin-fullerene electropolymers ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-03-11 — — US disclosed
US-20130239661-A1 USE OF DIAZONIUM SALTS FOR THE FORMATION OF THICK LAYERS ON AT LEAST ONE SURFACE OF A SUBSTRATE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-09-19 — — US disclosed
EP-2611773-A1 USE OF DIAZONIUM SALTS FOR THE FORMATION OF THICK LAYERS ON AT LEAST ONE SURFACE OF A SUBSTRATE Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2013-07-10 — — EP disclosed
WO-2012029035-A1 USE OF DIAZONIUM SALTS FOR THE FORMATION OF THICK LAYERS ON AT LEAST ONE SURFACE OF A SUBSTRATE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-03-08 — — WO disclosed
US-20100065123-A1 Electrically conducting porphyrin and porphyrin-fullerene electropolymers UNITED STATES DEPARTMENT OF ENERGY 2010-03-18 — — US disclosed
US-20100065123-A1 Electrically conducting porphyrin and porphyrin-fullerene electropolymers UNITED STATES DEPARTMENT OF ENERGY 2010-03-18 — — US disclosed
US-20100065123-A1 Electrically conducting porphyrin and porphyrin-fullerene electropolymers UNITED STATES DEPARTMENT OF ENERGY 2010-03-18 — — US disclosed
WO-2008109467-A1 ELECTRICALLY CONDUCTING PORPHYRIN AND PORPHYRIN-FULLERENE ELECTROPOLYMERS ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2008-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100065123-A1 Electrically conducting porphyrin and porphyrin-fullerene electropolymers HMBS, PPOX, SLC40A1 STAT3 1810/4885STAT1 3390/4885TOP1 3826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback