Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 17/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973592 | 0.87 | HSD11B1 (0.45) | NAMPTPIK3CDPIK3CAHRH3 | |
| SCHEMBL16208093 | 0.79 | HSD11B1 (0.47) | — | |
| SCHEMBL976942 | 0.76 | NAMPT (0.45) | NAMPTPIK3CDPIK3CAHRH3 | |
| SCHEMBL16208095 | 0.74 | HSD11B1 (0.60) | — | |
| SCHEMBL16208085 | 0.74 | HSD11B1 (0.51) | — | |
| SCHEMBL16208149 | 0.73 | HSD11B1 (0.36) | — | |
| SCHEMBL16208091 | 0.72 | HSD11B1 (0.58) | — | |
| SCHEMBL16208130 | 0.71 | HSD11B1 (0.37) | — | |
| SCHEMBL238252 | 0.71 | L3MBTL1 (0.56) | NAMPTHRH3 | |
| SCHEMBL16208203 | 0.71 | HSD11B1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238126-B1 | DERIVATIVES OF TETRAHYDROQUINOXALINE UREA, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2014-11-05 | — | — | EP | claimed |