Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BCL6 | P41182 | 1/20 | 0.47 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114516 | 0.82 | PKM (0.71) | KIF11LMNAPKM | |
| SCHEMBL28962166 | 0.82 | PKM (0.71) | KIF11LMNAPKM | |
| SCHEMBL16208480 | 0.81 | KIF11 (0.72) | KIF11CRBNNPC1PKM | |
| SCHEMBL516986 | 0.81 | KIF11 (0.67) | KIF11PGRMEN1NPC1KMT2A | |
| SCHEMBL16208500 | 0.79 | KIF11 (0.67) | KIF11CRBNPKM | |
| SCHEMBL16208502 | 0.79 | KIF11 (0.67) | KIF11CRBNPKM | |
| SCHEMBL25875012 | 0.79 | KIF11 (0.65) | KIF11CRBNMEN1KMT2ABCL6 | |
| SCHEMBL16208495 | 0.78 | KIF11 (0.65) | KIF11CRBNNPC1PKM | |
| SCHEMBL16208513 | 0.76 | KIF11 (0.62) | KIF11CRBN | |
| SCHEMBL16208517 | 0.76 | KIF11 (0.72) | KIF11CRBNMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174745-A1 | Eg5 INHIBITOR | 国立大学法人京都大学 (JP) | 2014-10-30 | — | — | WO | disclosed |