Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.65 |
| ▸ | BCL6 | P41182 | 2/20 | 0.56 |
| ▸ | BCOR | Q6W2J9 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433644 | 0.85 | KIF11 (0.58) | KIF11BCL6BCORPKMCRBN | |
| SCHEMBL25875011 | 0.80 | MAPK14 (0.59) | KIF11CRBNULK1 | |
| SCHEMBL22159539 | 0.80 | CRBN (0.53) | KIF11BCL6BCORALDH1A1L3MBTL1 | |
| SCHEMBL22159513 | 0.80 | CRBN (0.68) | KIF11BCL6BCORALDH1A1L3MBTL1 | |
| SCHEMBL16208459 | 0.79 | KIF11 (1.00) | KIF11BCL6BCORPKMMEN1 | |
| SCHEMBL16208480 | 0.77 | KIF11 (0.72) | KIF11PKMCRBNULK1 | |
| SCHEMBL4225375 | 0.77 | MAPK14 (0.65) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL16208505 | 0.77 | KIF11 (0.67) | KIF11ULK1 | |
| SCHEMBL5286182 | 0.74 | MAPK1 (0.51) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL11506844 | 0.73 | ALDH1A1 (0.89) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192643-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192643-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | CRBN, RBX1, ADRM1 | KIF11 2826/4885BCL6 261/4885BCOR 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.