Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 1.00 |
| ▸ | ULK1 | O75385 | 5/20 | 0.55 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208449 | 0.93 | KIF11 (1.00) | KIF11ULK1TNIK | |
| SCHEMBL16208488 | 0.82 | KIF11 (1.00) | KIF11ULK1PKMPKLR | |
| SCHEMBL16208463 | 0.81 | KIF11 (1.00) | KIF11ULK1PKMPKLR | |
| SCHEMBL16208485 | 0.80 | KIF11 (0.85) | KIF11ULK1PKMPKLR | |
| SCHEMBL26088240 | 0.79 | KIF11 (0.65) | KIF11ULK1TNIK | |
| SCHEMBL16208470 | 0.78 | ULK1 (0.66) | KIF11ULK1 | |
| SCHEMBL2238253 | 0.78 | KIF11 (0.77) | KIF11PKMPKLR | |
| SCHEMBL16208464 | 0.78 | KIF11 (0.75) | KIF11ULK1PKMPKLR | |
| SCHEMBL16208446 | 0.77 | KIF11 (0.64) | KIF11ULK1TNIK | |
| SCHEMBL16208482 | 0.76 | KIF11 (0.61) | KIF11ULK1TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174745-A1 | Eg5 INHIBITOR | 国立大学法人京都大学 (JP) | 2014-10-30 | — | — | WO | disclosed |