Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.61 |
| ▸ | ULK1 | O75385 | 9/20 | 0.57 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208446 | 0.85 | KIF11 (0.64) | KIF11ULK1TNIKPTK2BPTK2 | |
| SCHEMBL16208464 | 0.79 | KIF11 (0.75) | KIF11ULK1 | |
| SCHEMBL16208470 | 0.77 | ULK1 (0.66) | KIF11ULK1PTK2BPTK2 | |
| SCHEMBL16208488 | 0.76 | KIF11 (1.00) | KIF11ULK1 | |
| SCHEMBL16208486 | 0.76 | KIF11 (1.00) | KIF11ULK1TNIK | |
| SCHEMBL17544974 | 0.75 | ULK1 (0.58) | KIF11ULK1PTK2BPTK2 | |
| SCHEMBL16208485 | 0.74 | KIF11 (0.85) | KIF11ULK1 | |
| SCHEMBL29575705 | 0.73 | PTK2B (0.82) | KIF11ULK1PTK2BPTK2 | |
| SCHEMBL17545058 | 0.73 | PTK2B (0.82) | KIF11ULK1PTK2BPTK2 | |
| SCHEMBL21374241 | 0.73 | ULK1 (0.77) | KIF11ULK1PTK2BPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174745-A1 | Eg5 INHIBITOR | 国立大学法人京都大学 (JP) | 2014-10-30 | — | — | WO | disclosed |