Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30946289 | 0.78 | KIF11 (0.63) | KIF11 | |
| SCHEMBL20660889 | 0.78 | KIF11 (0.63) | KIF11 | |
| SCHEMBL1921482 | 0.77 | KIF11 (0.70) | KIF11AKR1C3AKR1C2ALDH1A1IDH2 | |
| SCHEMBL394991 | 0.76 | KIF11 (0.70) | KIF11HTTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL16208489 | 0.74 | KIF11 (1.00) | KIF11HTTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL16208493 | 0.73 | KIF11 (0.60) | KIF11HTTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL3439833 | 0.72 | HTT (0.64) | KIF11HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6397413 | 0.72 | KIF11 (0.56) | KIF11HTTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL1921505 | 0.72 | KIF11 (0.64) | KIF11AKR1C3AKR1C2ALDH1A1IDH2 | |
| SCHEMBL1082200 | 0.71 | KIF11 (0.56) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174745-A1 | Eg5 INHIBITOR | 国立大学法人京都大学 (JP) | 2014-10-30 | — | — | WO | disclosed |