Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 1.00 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575928 | 0.79 | KIF11 (0.64) | KIF11KMT2AMEN1HTR1AHTR2C | |
| SCHEMBL31068659 | 0.79 | KIF11 (0.64) | KIF11KMT2AMEN1HTR1AHTR2C | |
| SCHEMBL1921482 | 0.75 | KIF11 (0.70) | KIF11AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL394991 | 0.75 | KIF11 (0.70) | KIF11AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL16208493 | 0.75 | KIF11 (0.60) | KIF11AKR1C3AKR1C2KMT2AHTT | |
| SCHEMBL16208519 | 0.74 | KIF11 (1.00) | KIF11AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL10338441 | 0.73 | PDE3B (0.60) | KIF11KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL1023114 | 0.71 | CMA1 (0.56) | KIF11KMT2AMEN1HTR1AHTR2C | |
| SCHEMBL6397413 | 0.71 | KIF11 (0.56) | KIF11AKR1C3AKR1C2KMT2AHTT | |
| SCHEMBL1921505 | 0.71 | KIF11 (0.64) | KIF11AKR1C3AKR1C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174745-A1 | Eg5 INHIBITOR | 国立大学法人京都大学 (JP) | 2014-10-30 | — | — | WO | disclosed |