SCHEMBL29201529

SCHEMBL29201529

O=c1cnc2ccccc2n1Cc1ccc(Br)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
GALR3 O60755 1/20 0.57
NR2F2 P24468 1/20 0.57
ALDH1A1 P00352 8/20 0.55
KDM4E B2RXH2 7/20 0.55
HPGD P15428 2/20 0.55
TDP1 Q9NUW8 1/20 0.54
NPSR1 Q6W5P4 3/20 0.53
TP53 P04637 1/20 0.53
LMNA P02545 3/20 0.51
TSHR P16473 3/20 0.51
RAB9A P51151 1/20 0.51
HSD17B10 Q99714 3/20 0.50
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HBB P68871 1/20 0.48
TBXA2R P21731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414257 0.88 MEN1 (0.72) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL16210700 0.88 MEN1 (0.72) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL29201531 0.87 MEN1 (0.71) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL29201530 0.87 KMT2A (0.71) MEN1KMT2AGALR3NR2F2ALDH1A1
SCHEMBL30050434 0.85 MEN1 (0.73) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL28595389 0.85 MEN1 (0.73) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL29201528 0.85 MEN1 (0.69) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL7225918 0.83 MEN1 (0.70) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL30934954 0.83 MEN1 (0.70) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL3714561 0.83 ALDH1A1 (0.52) MEN1KMT2AALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924194-A 7-Thiocyanoquinoxalinone compound and synthesis method thereof 延安大学 2024-04-26 CN disclosed